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RM43 Weed Killer Review

The RM43 Weed Killer claims to help you get rid of weeds quickly, but does it really work? The RM43 herbicide contains a 43-percent glyphosate complement (as mentioned in the title). This enables it to efficiently kill weeds at the root level. Many other labels operate by literally destroying the weed’s vegetative nature. You will be rid of the organisms for up to a year by removing them at the root.

43-Percent Glyphosate PlusFeatures of RM43 Weed Killer:

  • Kill weeds and prevents weeds for up to 1 year
  • Treats 4,324 sq. ft.
  • Can be used for total vegetation control or spot control of brush, vines and weedss


This substance is so powerful that it can even kill your healthy plants. If you have it on leaves, bushes, or vines, it can kill them from the root up, so be cautious. You won’t hurt any of your beneficial plants if you use this product successfully on weeds.

The RM43 is effective against weeds in areas other than the turf. Weeds are often found on sidewalks and in driveway cracks. They encroach on barns, gates, and gravel roads, among other things. Simply add it to the weeds as led in these areas for spot control.

You do not need to apply the product again for 1 year after you’ve applied it. This is a significant advantage for someone who does not wish to be eaten by weed removal. This product’s 2-component formula makes it one of the most competitive on the market.

Active Ingredients:

Glyphosate, isopropylamine salt 43.68%

Imazapyr, isopropylamine salt

Other Ingredients 55.54%
Total 100%

Active components

Glyphosate and Imazapyr are the active ingredients in RM43 concentrate. For absolute weed control, these non-selective herbicides act together to destroy most plants and trees.

Glyphosate functions by inhibiting the production of certain enzymes required for plant development. Glyphosate inhibits the shikimic acid pathway, a particular enzyme pathway required for plant growth and the growth of certain microorganisms.

Imazapyr is consumed by the plant’s leaves and roots. It spreads quickly through the plant, and gradually accumulates in the active growth zone. Imazapyr causes protein production to be disrupted in plants, as well as cell growth and DNA synthesis. It’s also water-soluble, but depending on the surface condition and moisture level, it will spread to areas where it wasn’t sprayed.


  • Kills all weeds to the roots;
  • The effects may last up to 1 year;
  • The coverage area is 17, 297 sq. ft.;
  • Good for many non-crop areas;
  • Total vegetation control;
  • Rainproof in 2 hours;
  • Includes pre-emergent and post-emergent components;

It results in 5 gallons of spot-treatment spray solution. This substance is available in 3 sizes: 0.25 gallon, 1 gallon, and 2.5 gallons. The largest 2.5-gallon container will treat 43,243 sq. ft. As a result, the commodity is very cost-effective. When fully reconstituted, the 1-gallon tub can treat 17,296 sq. ft. if you don’t need that many.

What weeds can it kill?

The RM43 Weed Killer controls a wide range of broadleaf weeds and vegetation in turfgrass.

A few weeds of many that can be destroyed with this RM43 product (check the full list on the label instructions): 

  • Bluegrass;
  • Buttercup;
  • Chickweed;
  • Clover;
  • Dandelion;
  • Wild garlic;
  • Ground ivy;

It may also cope with a few trees (stumps) and vines:

  • Cherry;
  • Ash;
  • Balsam apple;
  • Beech;
  • Birch;
  • Hazel;
  • Locust;
  • Poison ivy;
  • Pine;
  • Poison oak;
  • Raspberry;
  • Maple;
  • Oak;

By most reviews, this substance is less effective against drought-stressed weeds.

How to use it?

It’s easy to make a functioning approach with the RM43 herbicide. Simply mix in the necessary volume of water and you’re good to go. Furthermore, it has a higher shelf life than a functioning solution.

Anyone handling the product should use specific PPE, according to RM43. Please keep in mind that reading the mark carefully is crucial. The below are the exact directions taken straight from the label:

1) When applying on the bare ground: 

  • Hand-held sprayers, such as backpack sprayers, pump-up sprayers, or sprinkling cans, or ATV/Tractor fixed sprayers, can be used;
  • To make 1 to 10 gallons of spray solution, mix 7.4 fl. oz. (0.46 pints) of this substance with water;
  • Applications against actively developing weeds in the early summer would yield the best results;
  • Spray the mixture in a pattern throughout the field where complete weed control is required. To cover 1,000 square feet, mix 7.4 fl. oz. of the powder with 1 to 10 gallons of spray solution;

2) When applying for spot control on certain weeds, bushes and vines: 

  • Hand-held sprayers, such as backpack sprayers, pump-up sprayers, or sprinkling cans, or ATV/Tractor fixed sprayers, can be used;
  • Use 1 gallon of spray solution + 6 fl. oz. of this liquid. To wet the leaves of woody plants, spray it thoroughly;

How to achieve the maximum result: 

  • Apply to brush, vines, and weeds that are actively developing;
  • After the fruit forming, woody brush and vines are easier to control in late summer and fall;
  • Wait before complete leaf development until treating woody vines and brush that have been mowed or trimmed;
  • Grass, trees, and flowering weeds can’t be trimmed or mowed for 2 months after the RM43 treatment;
  • The maximum application rate for this substance is 2.5 gallons per 1 acre annually (no more than 7.4 fl. oz. per 1,000 sq. ft. annually);

When to use:

Weed control is given by RM43 concentrate both before and after emergence. This ensures you can apply it as a precautionary step to deter harmful weeds from breaking through the soil’s surface, as well as a cure after they’ve broken through.

The RM43 product is quite effective all year round. However, most gardeners recommend using it only in the early summer or late spring. Usually, it is the time when the weeds and trees are actively growing. Choose warm, non-windy and sunny days to spray it. When applying on vines and woody bushes, use it after the fruit formation – until late summer or fall. Use it on a sunny day with a temperature of at least 60 degrees Fahrenheit.

Where to use:

The RM43 Weed Killer is recommended for use on such non-crop areas: 

  • Roadsides;
  • Warehouse and barn areas;
  • Curbs and fences;
  • Sidewalks and driveways;
  • Parking zones;
  • Farmyards;
  • Brick walls and gravel paths;

Do not allow the product to runoff into suitable plants in the region. Weed control in hard clay soils can take longer than a year.

RM43 is suitable for streets, fencerows, gravel roads, parking areas, driveways, and around farm buildings and barns, as well as every other place that you want to spray once and be finished for up to a year.

How long does it take to work?

One of the advantages of using RM43 is how quickly it works. The formula rapidly spreads across the whole plant until consumed, and the target weed’s growth is suppressed shortly after interaction since plant protein production is inhibited. RM43 is consumed by both the roots and the foliage of plants. And it quickly stops susceptible weeds from growing.

And though visual signs can take time to emerge, the weed development ceases within 24 hours after a single application. Within 2 to 3 weeks, the susceptible weeds will begin to yellow or brown. The herbicidal effect would be accelerated in warm, moist environments rather than in cold, dry conditions.

According to some user reviews, the results of RM43 Weed Killer appear in such an order: 

  • After 36 hours – there are no visible changes;
  • After 1 week – the first signs of discoloration on treated weeds;
  • After 2 weeks – the destruction of the vegetation;

Tips for users: Within 2 hours of application, heavy rain or irrigation can wash this product off the leaves, necessitating a repeat application for effective control.

RM43 Weed Killer User Manual

Having problem? Download RM43 43-Percent Glyphosate Plus Weed Preventer Total Vegetation Control instructions.

Pros & Cons of RM43 Weed Killer

  • Powerful formula;
  • Fast performance;
  • Cost-effective;
  • Long shelf life;
  • Good price point;
  • Large coverage area;
  • Designed for non-crop vegetation control;
  • Simple to mix;
  • Ideal for fence rows, gravel paths, sidewalks, driveways, parking areas and around farm buildings and barns
  • Makes up to 53 gallons of spray solution for spot treatments
  • Kills weeds, grass and brush
  • RM43 weed killer is a quality weed preventer for your yard
  • Not for use around pets or kids;
  • May arrive leaking;
  • May kill beneficial plants;
  • Pricey for the small quantity;
  • No fast results

The RM43 Weed Killer is a strong, reliable weed killer. This product is perfect for places with many weeds, and it can save you a lot of money compared to employing a specialist. Another significant advantage to this scheme is that after a region has been handled, you can’t need to return for up to a year.

The Buyer’s Guide


You need a weed killer that is made to be safe and long-lasting since weeds are reducing the value of any garden and lawn. Testing the chemicals contained in the item is the first step in determining this. Since the main ingredients of RM43 are Glyphosate and Imazapyr (the powerful herbicides), it is considered an effective weed killer. 


When you buy a low-cost weed killer, it’s likely that it won’t withstand water. That means you should anticipate it to wash away as it rains. As a consequence, the job would be inefficient and unsustainable. Furthermore, they have the ability to pollute rivers. Purchasing RM43 ensures that you have a long-lasting quality that would not wash away.


You should have to take fair safety precautions for this product without going overboard.

A few safety tips to use when applying the RM43 product:

  • Always follow the manufacturer’s mixing and application instructions;
  • In hot weather, avoid spraying;
  • Do not use on new grass or trees that you choose to keep untouched;
  • After applying the product, wait at least 24 hours before watering your grass;
  • After applying the product, wait 2-3 days before mowing the lawn;
  • The further you add the product to the weeds, the quicker it can remove them;
  • When combining or spraying, do use necessary safety equipment such as goggles and gloves;
  • When spraying, keep pets and children out of the area;


How should you dilute the RM43 product?

There are 2 basic dilution ratios. To kill all the weeds to the ground, use a concentration of 7.4 ounces of this product per 1 gallon of clean water (up to 10 gallons). The maximum application rate of 7.4 ounces is per 10,000 sq. ft. (2.5 gallons per 1 acre) throughout a year. If you seek the spot dilution, you should mix 6 ounces of RM43 per 1 gallon of clean water. 

Does it really kill all weeds for good?

It is better to use RM43 around the areas where you can’t trim or mow. It may prevent the weeds and plants from regrowing for 1 year. You can even reseed the treated area after some time. 

Is it safe to spray RM43 on the roots and leaves?

Yes. The glyphosate acts best when it is absorbed through the leaves. You should spray it all over the foliage of the undesired vegetation. The product may also absorb through the root system for total vegetation control. After such a treatment, do not mow or cut the treated areas for 2 months. 

How does this product affect large trees?

While some consumers claim that it won’t kill crops, it’s best not to spray this solution on some plants you choose to keep developing. This product’s warning expressly states that it can not be used near trees or other plants that you choose to keep. Even if your trees are tall, the weed killer has a fair risk of harming them. It is not advised to use it around or on plants.

How much water to use for mixing with 1 ounce of RM43?

You’ll need at least 6 ounces of RM43 Weed Killer per every gallon of water you use. Still read and fulfill the product’s directions.

Video Guide: How To Use RM43 Weed Killer

Final thoughts 

Weeds can be easily killed by the RM43 weed killer, although they will not kill fast. RM43 is a mixture of 2 herbicides and a surfactant, as previously mentioned. You should expect superior outcomes with the RM43 weed killer. Save money by doing the job yourself rather than employing a specialist landscaper.